Key Publications Archive

Carcinoembryonic antigen-related cell adhesion molecule 1 inhibits MMP-9-mediated blood-brain-barrier breakdown in a mouse model for ischemic stroke.

Ludewig P, Sedlacik J, Gelderblom M, Bernreuther C, Korkusuz Y, Wagener C, Gerloff C, Fiehler J, Magnus T, Horst AK. Circ Res. 2013 Sep 27;113(8):1013-22. doi: 10.1161/CIRCRESAHA.113.301207. Epub 2013 Jun 18. PMID: 23780386

By Stefanie Discher|2022-04-26T16:24:10+02:00April 26th, 2022|Key Publications|Comments Off

Nanobodies that block gating of the P2X7 ion channel ameliorate inflammation.

Danquah W, Meyer-Schwesinger C, Rissiek B, Pinto C, Serracant-Prat A, Amadi M, Iacenda D, Knop JH, Hammel A, Bergmann P, Schwarz N, Assunção J, Rotthier W, Haag F, Tolosa E, Bannas P, Boué-Grabot E, Magnus T, Laeremans T, Stortelers C, Koch-Nolte F. Sci Transl Med. 2016 Nov 23;8(366):366ra162. doi: 10.1126/scitranslmed.aaf8463. PMID: 27881823

By Stefanie Discher|2022-04-26T16:24:03+02:00April 26th, 2022|Key Publications|Comments Off

Characterization of brain-derived extracellular vesicles reveals changes in cellular origin after stroke and enrichment of the prion protein with a potential role in cellular uptake.

Brenna S, Altmeppen HC, Mohammadi B, Rissiek B, Schlink F, Ludewig P, Krisp C, Schlüter H, Failla AV, Schneider C, Glatzel M, Puig B, Magnus T. J Extracell Vesicles. 2020 Aug 27;9(1):1809065. doi: 10.1080/20013078.2020.1809065. PMID: 32944194

By Stefanie Discher|2022-04-26T16:23:53+02:00April 26th, 2022|Key Publications|Comments Off

Magnetic Particle Imaging for Real-Time Perfusion Imaging in Acute Stroke.

Ludewig P, Gdaniec N, Sedlacik J, Forkert ND, Szwargulski P, Graeser M, Adam G, Kaul MG, Krishnan KM, Ferguson RM, Khandhar AP, Walczak P, Fiehler J, Thomalla G, Gerloff C, Knopp T, Magnus T. ACS Nano. 2017 Oct 24;11(10):10480-10488. doi: 10.1021/acsnano.7b05784. Epub 2017 Oct 4. PMID: 28976180

By Stefanie Discher|2022-04-26T16:23:40+02:00April 26th, 2022|Key Publications|Comments Off

Monitoring Intracranial Cerebral Hemorrhage Using Multicontrast Real-Time Magnetic Particle Imaging.

Szwargulski P, Wilmes M, Javidi E, Thieben F, Graeser M, Koch M, Gruettner C, Adam G, Gerloff C, Magnus T, Knopp T, Ludewig P. ACS Nano. 2020 Oct 27;14(10):13913-13923. doi: 10.1021/acsnano.0c06326. Epub 2020 Sep 25.

By Stefanie Discher|2022-04-26T16:23:20+02:00April 26th, 2022|Key Publications|Comments Off

IL-23 (Interleukin-23)-Producing Conventional Dendritic Cells Control the Detrimental IL-17 (Interleukin-17) Response in Stroke.

Gelderblom M, Gallizioli M, Ludewig P, Thom V, Arunachalam P, Rissiek B, Bernreuther C, Glatzel M, Korn T, Arumugam TV, Sedlacik J, Gerloff C, Tolosa E, Planas AM, Magnus T. Stroke. 2018 Jan;49(1):155-164. doi: 10.1161/STROKEAHA.117.019101. Epub 2017 Dec 6. PMID: 29212740

By Stefanie Discher|2022-04-26T16:23:13+02:00April 26th, 2022|Key Publications|Comments Off

Temporal and spatial dynamics of cerebral immune cell accumulation in stroke.

Gelderblom M, Leypoldt F, Steinbach K, Behrens D, Choe CU, Siler DA, Arumugam TV, Orthey E, Gerloff C, Tolosa E, Magnus T. Stroke. 2009 May;40(5):1849-57. doi: 10.1161/STROKEAHA.108.534503. Epub 2009 Mar 5. PMID: 19265055

By Stefanie Discher|2022-04-26T16:23:03+02:00April 26th, 2022|Key Publications|Comments Off

Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke.

Gelderblom M, Weymar A, Bernreuther C, Velden J, Arunachalam P, Steinbach K, Orthey E, Arumugam TV, Leypoldt F, Simova O, Thom V, Friese MA, Prinz I, Hölscher C, Glatzel M, Korn T, Gerloff C, Tolosa E, Magnus T. Blood. 2012 Nov 1;120(18):3793-802. doi: 10.1182/blood-2012-02-412726. Epub 2012 Sep 13.

By Stefanie Discher|2022-04-26T16:23:07+02:00April 26th, 2022|Key Publications|Comments Off